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bp0016cpr14 | Embryonic and Placental Development | CPR2001

Functional analysis of autocrine and paracrine signalling at the uterine–conceptus interface in pigs

Jaeger L. A. , Johnson L. A. , Ka H. , Gadow J. G. , Burghardt R. C. , Spencer T. E. , Bazer F.W.

The complexity of implantation necessitates intimate dialogue between conceptus and maternal cells, and precise coordination of maternal and conceptus signalling events. Maternal and conceptus-derived steroid hormones, growth factors and cytokines, as well as integrins and their ligands, have important and inter-related roles in mediating adhesion between apical aspects of conceptus trophectoderm and maternal uterine luminal epithelium that leads to formation of an epithelioch...